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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
14.85
Human Site:
T24
Identified Species:
21.78
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
T24
R
I
R
A
F
P
M
T
M
D
E
K
Y
V
N
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
D24
K
Y
V
N
S
I
W
D
L
L
K
N
A
I
Q
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
R24
N
A
I
Q
E
I
Q
R
K
N
N
S
G
L
S
Dog
Lupus familis
XP_534586
746
86477
R24
N
A
I
Q
E
I
Q
R
K
N
N
S
G
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
T24
R
I
R
A
F
P
M
T
M
D
E
K
Y
V
N
Rat
Rattus norvegicus
Q9JJ31
780
90872
V26
W
D
F
M
R
P
I
V
L
K
L
L
R
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
Chicken
Gallus gallus
XP_422620
768
88957
T24
R
I
R
A
F
P
M
T
M
D
E
K
Y
V
N
Frog
Xenopus laevis
Q6DE95
768
88933
T24
R
I
R
A
F
P
M
T
M
D
E
K
Y
V
N
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
D24
R
A
F
P
M
T
M
D
E
K
Y
V
N
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
E25
D
I
W
S
E
L
V
E
G
I
M
Q
V
F
E
Honey Bee
Apis mellifera
XP_625079
767
89385
E24
A
F
P
T
T
M
D
E
K
Y
V
E
S
I
W
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
E24
P
F
M
A
T
I
D
E
Q
Y
V
T
Q
T
W
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
G28
K
L
K
R
I
L
E
G
L
N
E
P
A
F
D
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
S25
S
E
E
S
F
E
E
S
W
E
T
V
K
Y
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
0
0
0
N.A.
100
6.6
N.A.
0
100
100
13.3
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
26.6
20
20
N.A.
100
20
N.A.
0
100
100
13.3
N.A.
26.6
13.3
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
19
0
32
0
0
0
0
0
0
0
0
13
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
13
13
0
25
0
0
0
0
7
% D
% Glu:
0
7
7
0
19
7
13
19
7
7
32
7
0
0
13
% E
% Phe:
0
13
13
0
32
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
32
13
0
7
25
7
0
0
7
0
0
0
13
7
% I
% Lys:
13
0
7
0
0
0
0
0
19
13
7
25
7
0
0
% K
% Leu:
0
7
0
0
0
13
0
0
19
7
7
7
0
13
0
% L
% Met:
0
0
7
7
7
7
32
0
25
0
7
0
0
0
0
% M
% Asn:
13
0
0
7
0
0
0
0
0
19
13
7
7
7
25
% N
% Pro:
7
0
7
7
0
32
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
13
0
0
13
0
7
0
0
7
7
7
7
% Q
% Arg:
32
0
25
7
7
0
0
13
0
0
0
0
7
0
0
% R
% Ser:
7
0
0
13
7
0
0
7
0
0
0
13
7
0
13
% S
% Thr:
0
0
0
7
13
7
0
25
0
0
7
7
0
7
0
% T
% Val:
0
0
7
0
0
0
7
7
0
0
13
13
7
25
0
% V
% Trp:
7
0
7
0
0
0
7
0
7
0
0
0
0
0
13
% W
% Tyr:
0
7
0
0
0
0
0
0
0
13
7
0
25
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _